Malignant melanoma in a equine: report of a case
DOI:
https://doi.org/10.22579/22484817.596Keywords:
Melanoma, excisional biopsy, eyelid, horseAbstract
The aim of this study is to report a case of melanoma in a quarter-mile horse cross, male, 10 years of age, moor color, which was taken to the clinic of the Universidad de los Llanos by a mass in the right eyelid which prevented his vision for that eye in March 2010. In this case report, we emphasize on clinical signs, laboratory tests such as CBC, excisional biopsy and histopathology, and introduced to animal treatment.
References
Dummer, R.; Hauschild, A.; Henseler, T. et al. Combined interferon - and interleukin - 2 as adjuvant treatment for melanoma. Lancet, London, 352: 908-909. 1998.
Essner, R.; Belhocine, T.; Scott, A. M.; Even-Sapir E. Novel imaging techniques in melanoma. Surg Oncol Clin N Am.,15 (2): 253-83. 2006.
Goetz, T. E.; Ogilvie, G. K.; Keegan, K. G. et al. Cimetidine for treatment of melanomas in three horses. Journal of the American Veterinary Medical Association, Schaumburg. 196 (3): 449-452. 1990.
Hsu, M. Y.; Meier, F. E.; Nesbit, M. et al. E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am Journal Pathology, 156: 1515-1525. 2000.
Huang S.; Ullrich, S. E.; Bar-Eli, M. Regulation of tumor growth and metastasis by interleukin-10: the melanoma experience. Journal of Interferon Cytokine, 19: 697-703. 1999.
Lazar M., E.; Hegyesi, H.; Toth, S.; Falus, A. Autocrine and paracrine regulation by cytokines and growth factors in melanoma. Journal of Cytokine, 12: 547-554. 2000.
Meier, F.; Nesbit, M.; Hsu, M. Y. et al. Human melanoma progression in skin reconstructs: biological significance of bFGF. Am Journal of Pathology, 156: 193-200. 2000.
Meier, F.; Satyamoorthy, K. Nesbit, M. et al. Molecular events in melanoma development and progression. Front Biosci, 3: 1005-1010. 1998.
Ritt, M. G.; Wojcieszyn, J.; Modiano, J. F. Functional loss of p21/Waf-1 in a case of benign canine multicentric melanoma. Veterinary Pathology, 35: 94-101. 1998.
Rowe, E. L.; Sullins, K. E. Excision as treatment of dermal melanomatosis in horses: 11 cases (1994 - 2000). Journal of the American Veterinary Medical Association, Schaumburg. 225 (1): 94-96. 2004.
Sanders, D. S.; Blessing, K.; Hassan, G. A. et al. Alterations in cadherin and catenin expression during the biological progression of melanocytic tumours. Mol Pathol, 52: 151-157. 1999.
Seltenhammer, M. H.; Simhofer, H.; Scherzer, S. et al. Equine melanoma in a population of 296 grey Lipizzaner horses. Equine Veterinary Journal, London. 35 (2): 153-157. 2003.
Smith, S. H.; Goldschmidt, M. H.; McManus, P. M. A comparative review of melanocitic neoplasms. Veterinary Pathology, Washington. 39: 651-678. 2002.
Vidal-Vanaclocha, F.; Fantuzzi, G.; Mendoza, L. et al. IL-18 regulates IL-1beta–dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1. Proc Natl Acad Sci USA. 97: 734-739. 2000.
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